What do we do?

We conduct pioneering research on urease inhibitors, with a dual focus on enhancing agricultural productivity through the development of advanced fertilizers, and devising innovative therapeutic strategies to combat infections caused by urease-producing pathogenic microorganisms. Our aim is to translate scientific knowledge into practical applications that promote both environmental sustainability and public health.

Agricultural Applications

We investigate and develop novel classes of compounds aimed at improving the efficiency of nitrogen-based fertilizers. By targeting the urease enzyme present in soils, our research seeks to minimize nitrogen losses, thereby reducing environmental pollution and enhancing nutrient availability for crops. This approach not only promotes more sustainable agricultural practices but also contributes to increased crop yields. Ultimately, our goal is to provide innovative, science-driven solutions that address the global challenges of food security and environmental sustainability.

Clinical Applications

Our research also delves into the critical role of urease in human health, with a particular focus on its involvement in the pathogenesis of urease-driven microbial infections. Given the growing concern over antibiotic resistance, we are investigating potential urease inhibitors as alternative or complementary therapeutic strategies. By targeting the urease enzyme, our studies aim to develop novel treatment options that could enhance the effectiveness of existing therapies, reduce reliance on antibiotics, and improve patient outcomes. Ultimately, our work seeks to contribute to more sustainable and effective approaches in the management of urease-related microbial diseases, addressing both the immediate and long-term challenges of antimicrobial resistance in clinical settings.